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The effects of oxytocin and galantamine on objectively-defined vocal and facial expression: Data from the CIDAR study

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As part of the Centers for InterventionDevelopment and Applied Research (CIDAR) initiative funded by the National Institute of Mental Health, galantamine and oxytocin were included in a three-arm, six week… Click to show full abstract

As part of the Centers for InterventionDevelopment and Applied Research (CIDAR) initiative funded by the National Institute of Mental Health, galantamine and oxytocin were included in a three-arm, six week randomly controlled trial (ClinicalTrials.gov NCT01012167). Both medications are associated with mild side effect profiles (Hansen et al., 2008; Oya et al., 2016), are relatively inexpensive, and have shown efficacy in at least some studies (Lee et al., 2013). Unfortunately, data from the CIDAR trial failed to find significant improvements in negative symptom severity or cognitive functioning with either galantamine or oxytocin compared to placebo using standard clinical rating scales or neuropsychological test batteries (Buchanan et al., 2016). The present study reanalyzed these data using computerized measures of

Keywords: data cidar; study; effects oxytocin; cidar; oxytocin galantamine

Journal Title: Schizophrenia Research
Year Published: 2017

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