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Evaluation of the antioxidant and cytotoxic activities of zinc oxide nanoparticles synthesized using scutellaria baicalensis root

Abstract The authors describe a simple green method for the preparation of zinc oxide nanoparticles (ZnONPs) using the aqueous root extract of Scutellaria baicalensis. The synthesized ZnONPs were characterized by… Click to show full abstract

Abstract The authors describe a simple green method for the preparation of zinc oxide nanoparticles (ZnONPs) using the aqueous root extract of Scutellaria baicalensis. The synthesized ZnONPs were characterized by UV-Vis spectroscopy, FTIR, TEM, SEM and EDX. They were spherical in shape and with sizes ranging from 33.14 to 99.03 nm. The ZnONPs produced exhibited significant free radical scavenging effects. An in-vitro study showed a dose-dependent cytotoxic effect on HeLa cells.

Keywords: scutellaria baicalensis; cytotoxic; oxide nanoparticles; root; zinc oxide

Journal Title: Scientific African
Year Published: 2019

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