Abstract A new family of well-defined NHC-Pd complexes immobilised onto silica, alumina and titania is reported. The catalysts display activity and recyclability in the Sonogashira cross-coupling reactions under batch and… Click to show full abstract
Abstract A new family of well-defined NHC-Pd complexes immobilised onto silica, alumina and titania is reported. The catalysts display activity and recyclability in the Sonogashira cross-coupling reactions under batch and continuous flow conditions. Under batch conditions the new catalytic systems were recycled up to four times with yields over 80%. These catalysts have a broad substrate scope of different aryl bromides and alkynes. The titania-supported catalysts show good conversions under continuous flow conditions at least over 8 h on stream using MeOH as solvent.
               
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