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The Notch ligand DLL4 has key roles during embryonic development of different tissues, but most of the data comes from animal models. Here we describe the generation and characterization of… Click to show full abstract
The Notch ligand DLL4 has key roles during embryonic development of different tissues, but most of the data comes from animal models. Here we describe the generation and characterization of 2 human Pluripotent Stem Cell (hPSC) lines that overexpress DLL4, as well as the two corresponding control hPSC lines. DLL4 expression can be detected at the mRNA and protein level, and does not affect the pluripotency of the cells. These hPSC lines can be used to study the role of DLL4 during human embryonic development.
Keywords:
ligand dll4;
notch ligand;
control hpsc;
hpsc
Journal Title: Stem cell research
Year Published: 2017
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Journal Title: Stem cell research
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!