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Best’s disease (BD) is an inherited retinal degenerative disease caused by mutations in BEST1 gene. A human induced pluripotent stem cell (iPSC) line has been generated with integration-free Sendai virus… Click to show full abstract
Best’s disease (BD) is an inherited retinal degenerative disease caused by mutations in BEST1 gene. A human induced pluripotent stem cell (iPSC) line has been generated with integration-free Sendai virus method from peripheral blood mononuclear cells (PBMCs) of a BD patient carrying c.888C > A mutation in BEST1 gene. This cell line may serve as a model for the study of pathogenesis of BD.
Keywords:
stem cell;
line;
disease;
best1 gene
Journal Title: Stem cell research
Year Published: 2019
Link to full text (if available)
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Journal Title: Stem cell research
Year Published: 2019
Link to full text (if available)
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recommendations!