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In this study, we generated 6 induced pluripotent stem cell (iPSC) lines derived from dermal fibroblasts of patients with sporadic amyotrophic lateral sclerosis (sALS). The fibroblasts were reprogrammed using non-integrating… Click to show full abstract
In this study, we generated 6 induced pluripotent stem cell (iPSC) lines derived from dermal fibroblasts of patients with sporadic amyotrophic lateral sclerosis (sALS). The fibroblasts were reprogrammed using non-integrating Sendai viruses containing four reprogramming factors OCT3/4, SOX2, KLF4 and C-MYC. The iPSC lines displayed normal molecular karyotype, expressed pluripotency markers and were capable of differentiating into three embryonic germ layers.
Keywords:
nuigi044;
stem cell;
nuigi043 nuigi043;
ipsc lines;
nuigi044 nuigi044;
induced pluripotent
Journal Title: Stem cell research
Year Published: 2019
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Journal Title: Stem cell research
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!