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Toll-like receptor 7 (TLR7) is a member of the toll-like receptor (TLR) family that is essential in the innate immune system. In this study, we established a heterozygous TLR7 knockout… Click to show full abstract
Toll-like receptor 7 (TLR7) is a member of the toll-like receptor (TLR) family that is essential in the innate immune system. In this study, we established a heterozygous TLR7 knockout H9 cell line using CRISPR/Cas9. TLR7 knockout H9 cells maintained their pluripotency and exhibited the ability to differentiate into the three germ layers without any karyotype abnormalities.
Keywords:
generation tlr7;
line;
crispr cas9;
using crispr;
knockout
Journal Title: Stem cell research
Year Published: 2020
Link to full text (if available)
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Journal Title: Stem cell research
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!