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Familial exudative vitreoretinopathy (FEVR) is an autosomal dominant genetic disease. An induced pluripotent stem cell line (EHTJUi002-A) was generated from umbilical cord blood mononuclear cells (UCBMCs) of a neonate with… Click to show full abstract
Familial exudative vitreoretinopathy (FEVR) is an autosomal dominant genetic disease. An induced pluripotent stem cell line (EHTJUi002-A) was generated from umbilical cord blood mononuclear cells (UCBMCs) of a neonate with heterozygous mutation of p.W226X(c.678G>A) in the FZD4 gene. This iPSC model offers a very valuable resource to study the pathological mechanism of FEVR in vitro.
Keywords:
exudative vitreoretinopathy;
stem cell;
pluripotent stem;
induced pluripotent;
stem
Journal Title: Stem cell research
Year Published: 2020
Link to full text (if available)
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Journal Title: Stem cell research
Year Published: 2020
Link to full text (if available)
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recommendations!