LAUSR

oop adjusted the laser power. 8 subjects participated in this study. timulations were applied on the dorsum side and in the palm of the and. Subjects were instructed to continuously rate the pain intenity. First the subject was stimulated using both a rising 35–45 ◦C taircase and a decreasing 45–35 ◦C staircase in both skin types; ach staircase step was 1 ◦C and lasted for 15 s. Offset analgesia was ested by stimulating the hairy skin on the dorsum of the hand using wo sequential temperature plateaus (48–48 ◦C, 48–49 ◦C, 49–48 ◦C nd 49–49 ◦C). Each plateau was held for 5 s. esults: For the staircase stimulations identical surface temperaures were perceived significantly higher in glabrous than in hairy kin (p < 0.001). The offset analgesia test showed that a decrease n temperature from 49 to 48 ◦C evoked a drop in the pain ratng which was significantly lower than observed during a 48–48 ◦C timulation (p < 0.001) indicating offset analgesia. onclusion: A non-contact thermal stimulator is able to evoke ffset analgesia. Furthermore, it was noted that a high penetraion laser causes higher pain ratings in glabrous skin than in hairy kin—a relationship which is opposite to low penetration lasers CO2 laser) and contact heat stimulation.