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For a highly beneficial mutant $A$ entering a randomly reproducing population of constant size, we study the situation when a second beneficial mutant $B$ arises before $A$ has fixed. If… Click to show full abstract
For a highly beneficial mutant $A$ entering a randomly reproducing population of constant size, we study the situation when a second beneficial mutant $B$ arises before $A$ has fixed. If the selection coefficient of $B$ is greater than the selection coefficient of $A$, and if $A$ and $B$ can recombine at some rate $\rho$, there is a chance that the double beneficial mutant $AB$ forms and eventually fixes. We give a convergence result for the fixation probability of $AB$ and its fixation time for large selection coefficients.
Keywords:
fixation probability;
beneficial mutant;
time
Journal Title: Stochastic Processes and their Applications
Year Published: 2018
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Journal Title: Stochastic Processes and their Applications
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!