Photo by nci from unsplash
CRISPR-Cas9 has been touted for therapeutic genome editing, but limitations include inefficient correction of disease-causing mutations and off-target mutagenesis. In the latest issue of Cell, Liao et al. (2017) show that… Click to show full abstract
CRISPR-Cas9 has been touted for therapeutic genome editing, but limitations include inefficient correction of disease-causing mutations and off-target mutagenesis. In the latest issue of Cell, Liao et al. (2017) show that a modified version of CRISPR-Cas9 can target and activate key therapeutic genes in vivo without altering DNA sequence identity.
Keywords:
heat therapeutic;
therapeutic epigenome;
turning heat;
epigenome editing;
cell
Journal Title: Cell stem cell
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Cell stem cell
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!