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Living Up to the Hype: Protein Synthesis Promotes Hypertranscription in Embryonic Stem Cells.

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The rapid proliferation and unlimited self-renewal of embryonic stem cells depends upon a permissive chromatin landscape that enables hypertranscription. In this issue of Cell Stem Cell, Bulut-Karslioglu et al. report that… Click to show full abstract

The rapid proliferation and unlimited self-renewal of embryonic stem cells depends upon a permissive chromatin landscape that enables hypertranscription. In this issue of Cell Stem Cell, Bulut-Karslioglu et al. report that euchromatin and transcriptional output are enhanced by protein synthesis in embryonic stem cells (Bulut-Karslioglu et al., 2018).

Keywords: cell; embryonic stem; protein synthesis; stem; stem cells; hypertranscription

Journal Title: Cell stem cell
Year Published: 2018

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