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Crinkle-Cut Brain Organoids.

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In large mammalian brains, including those of humans, the surface of the cortex is highly folded. How these convolutions form is still unclear, but recent work in Nature Physics by… Click to show full abstract

In large mammalian brains, including those of humans, the surface of the cortex is highly folded. How these convolutions form is still unclear, but recent work in Nature Physics by Karzbrun et al. (2018) supports a mechanism involving differential surface swelling combined with internal constraint.

Keywords: brain organoids; crinkle cut; cut brain

Journal Title: Cell stem cell
Year Published: 2018

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