LAUSR.org creates dashboard-style pages of related content for over 1.5 million academic articles. Sign Up to like articles & get recommendations!

Synthesis of novel hybrid steroid dimers by BF3·Et2O-catalyzed aldol condensation of 2-formyl-estradiol diacetate and steroid sapogenins

Photo from wikipedia

Graphical abstract Figure. No Caption available. HighlightsAldol condensation of an estrogen and steroid sapogenin acetates led to steroid dimers.Four new hybrid steroid dimers are described.The estrogenic core is attached to… Click to show full abstract

Graphical abstract Figure. No Caption available. HighlightsAldol condensation of an estrogen and steroid sapogenin acetates led to steroid dimers.Four new hybrid steroid dimers are described.The estrogenic core is attached to the side chain of the steroid sapogenin. Abstract BF3·Et2O‐catalyzed aldol condensation of steroid sapogenins with 2‐formyl‐estradiol diacetate afforded two novel classes of steroid dimers in which an estrogenic core is attached to the spirostanic side chain of an steroid sapogenin through an exocyclic double bond in position C‐23, or through a spiro centre in C‐22.

Keywords: hybrid steroid; steroid; steroid dimers; bf3 et2o; et2o catalyzed; condensation

Journal Title: Steroids
Year Published: 2017

Link to full text (if available)


Share on Social Media:                               Sign Up to like & get
recommendations!

Related content

More Information              News              Social Media              Video              Recommended



                Click one of the above tabs to view related content.