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Clamp loaders such as Ctf18-RFC assist DNA replication by loading the PCNA clamp onto DNA. In this issue of Structure, Grabarczyk et al. (2018) reveal that a hook-like structure formed by… Click to show full abstract
Clamp loaders such as Ctf18-RFC assist DNA replication by loading the PCNA clamp onto DNA. In this issue of Structure, Grabarczyk et al. (2018) reveal that a hook-like structure formed by the unique Dcc1 and Ctf8 subunits mediates the interaction of Ctf18-RFC with the leading strand DNA polymerase ɛ.
Keywords:
rfc loading;
roles ctf18;
clamp;
ctf18 rfc;
loading clamp;
dual roles
Journal Title: Structure
Year Published: 2018
Link to full text (if available)
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Journal Title: Structure
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!