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A tail goes viral by forming an anchor and a tether.

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In this issue of Structure, Aiyer et al. (2021) report NMR structures of BET:MLV IN complexes, highlighting a role for the disordered tail domain of MLV IN in viral integration. These… Click to show full abstract

In this issue of Structure, Aiyer et al. (2021) report NMR structures of BET:MLV IN complexes, highlighting a role for the disordered tail domain of MLV IN in viral integration. These studies expand the understanding of molecular recognition polymorphism in BET complexes and offer insight into cancer and antiviral therapeutics.

Keywords: anchor tether; viral forming; goes viral; tail; forming anchor; tail goes

Journal Title: Structure
Year Published: 2021

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