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Surgical margins in gastric cancer T2 and T3 and its relationship with recurrence and overall survival at 5 years.

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INTRODUCTION Surgical resection is the potentially curative treatment in gastric cancer. However, definitive surgical margins are controversial. MATERIAL AND METHODS We conducted a retrospective, observational study. All patients with gastric… Click to show full abstract

INTRODUCTION Surgical resection is the potentially curative treatment in gastric cancer. However, definitive surgical margins are controversial. MATERIAL AND METHODS We conducted a retrospective, observational study. All patients with gastric cancer treated with surgery of T2 and T3, tumors without involvement of the esophagogastric junction and without neoadjuvant treatment were included. RESULTS A total of 70 patients were included. 44 men (62.9%) and 26 women (37.1%). In multivariate analysis, depth of the invasion (T2 vs T3), lymphadenectomy and more than 5 positive nodes were independent factors for recurrence at 5 years. Depth of the invasion (T2 vs T3), intra-abdominal metastases and recurrence were independent factors of overall survival at 5 years. ROC analysis did not show a definitive surgical margin with better 5-year overall survival and lower recurrence. CONCLUSIONS In patients with gastric cancer T2 and T3, surgical margin did not affect 5-year overall survival or recurrence rate. Other factors are associated with recurrence and 5-year overall survival at 5 years, regardless of the distance from the tumor to the margin.

Keywords: gastric cancer; overall survival; survival years; recurrence

Journal Title: Surgical oncology
Year Published: 2020

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