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A new selective probe with a quinoxalinone structure, QP-1, has been developed for detection of Cys from biothiols. QP-1 features superb selectivity to Cys and a wide pH range. QP-1… Click to show full abstract
A new selective probe with a quinoxalinone structure, QP-1, has been developed for detection of Cys from biothiols. QP-1 features superb selectivity to Cys and a wide pH range. QP-1 has selectivity to Cys over Hcy, GSH, other amino acids and ions. HRMS spectra confirmed that the detection process was a conjugate addition-addition-elimination reaction. Moreover, QP-1 has been successfully applied in the imaging of Cys in living cells. Finally, QP-1 has been used to detect Cys in rat urine samples.
Keywords:
cys;
quinoxalinone structure;
probe quinoxalinone;
new selective
Journal Title: Talanta
Year Published: 2018
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Journal Title: Talanta
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!