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Amplification-free profiling of microRNA-122 biomarker in DILI patient serums, using the luminex MAGPIX system.

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Dynamic chemical labelling is a single-base specific method to enable detection and quantification of micro-Ribonucleic Acids in biological fluids without extraction and pre-amplification. In this study, dynamic chemical labelling was… Click to show full abstract

Dynamic chemical labelling is a single-base specific method to enable detection and quantification of micro-Ribonucleic Acids in biological fluids without extraction and pre-amplification. In this study, dynamic chemical labelling was combined with the Luminex MAGPIX system to profile levels of microRNA-122 biomarker in serum from patients with Drug-Induced Liver Injury.

Keywords: microrna 122; 122 biomarker; magpix system; luminex magpix; amplification

Journal Title: Talanta
Year Published: 2020

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