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Nuclear pore complexes (NPCs) have a conserved, but poorly understood, role in transcriptional regulation. Recently, in Developmental Cell, Raices et al. argued that tissue-specific nuclear pore proteins (Nups) act as… Click to show full abstract
Nuclear pore complexes (NPCs) have a conserved, but poorly understood, role in transcriptional regulation. Recently, in Developmental Cell, Raices et al. argued that tissue-specific nuclear pore proteins (Nups) act as scaffolds that recruit the transcription factor Mef2C to the NPC, promoting transcription of NPC-associated genes during muscle development.
Keywords:
transcription;
pore complexes;
complexes scaffold;
scaffold regulating;
nuclear pore;
pore
Journal Title: Trends in cell biology
Year Published: 2017
Link to full text (if available)
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Journal Title: Trends in cell biology
Year Published: 2017
Link to full text (if available)
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recommendations!