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Yeast and Human Nuclear Pore Complexes: Not So Similar After All.

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Nucleoporin subunits that generate the nuclear pore complex (NPC) are highly conserved in evolution. High-resolution structures of the NPC are available, but the actual NPC composition in yeast has only… Click to show full abstract

Nucleoporin subunits that generate the nuclear pore complex (NPC) are highly conserved in evolution. High-resolution structures of the NPC are available, but the actual NPC composition in yeast has only been quantified recently. Two studies reveal major differences between species, suggesting high flexibility in NPC structures during evolution.

Keywords: complexes similar; pore complexes; human nuclear; nuclear pore; yeast human; pore

Journal Title: Trends in cell biology
Year Published: 2018

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