Photo from archive.org
Abstract A new 1,8-naphthalimide derivative (NAD) was synthesized and employed as a highly sensitive and selective probe for the detection of cysteine (Cys) and Cu2+. The terminal olefin of NAD… Click to show full abstract
Abstract A new 1,8-naphthalimide derivative (NAD) was synthesized and employed as a highly sensitive and selective probe for the detection of cysteine (Cys) and Cu2+. The terminal olefin of NAD could react with Cys and resulting in fluorescence quenching, with the adding of Cu2+, the schiff base unit of NAD could coordinate with Cu2+ and lead to a highly selective fluorescence “turn-on” response. The detection limits reached as low as 25 nM for Cys and 11 nM for Cu2+. In addition, the NAD probe can be further applied to cells imaging owing to its photostability and low cytotoxicity.
Journal Title: Tetrahedron
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!