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Abstract Aminocarbonylation of alkenyl and aryl iodides in the presence of 4-amino-4H-1,2,4-triazole as N-nucleophile was carried out in the presence of palladium catalysts. Both types of substrates have shown high… Click to show full abstract
Abstract Aminocarbonylation of alkenyl and aryl iodides in the presence of 4-amino-4H-1,2,4-triazole as N-nucleophile was carried out in the presence of palladium catalysts. Both types of substrates have shown high chemoselectivity toward carboxamides, i.e. practically no double carbon monoxide insertion resulting in 2-ketocarboxamides took place. The results have been rationalised on the basis of mechanistic aspects of aminocarbonylation.
Keywords:
triazolyl carboxamides;
high yielding;
synthesis triazolyl;
yielding synthesis;
aminocarbonylation;
palladium
Journal Title: Tetrahedron
Year Published: 2017
Link to full text (if available)
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Journal Title: Tetrahedron
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!