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Abstract DIPEA-promoted one-pot synthesis of perfluoroalkylated indolizinylphosphonates by the reaction of pyridines 1, bromomethyl ketones 2 with perfluoroalkynylphosphonates 3 is described. This procedure is compatible with a broad range of… Click to show full abstract
Abstract DIPEA-promoted one-pot synthesis of perfluoroalkylated indolizinylphosphonates by the reaction of pyridines 1, bromomethyl ketones 2 with perfluoroalkynylphosphonates 3 is described. This procedure is compatible with a broad range of functional groups in both pyridines and ketones with good yields. The reaction proceeds through a tandem C N bond formation followed by an intramolecular cyclization.
Keywords:
perfluoroalkylated indolizinylphosphonates;
dipea promoted;
one pot;
promoted one;
synthesis perfluoroalkylated
Journal Title: Tetrahedron
Year Published: 2018
Link to full text (if available)
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Journal Title: Tetrahedron
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!