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Abstract Friedel-Crafts reaction of 1-(N-acylamino)alkyltriarylphosphonium salts with arenes or heteroarenes without the need for any catalyst provided access to a wide range of biologically interesting N-(1-arylalkyl)amides or 1-arylalkylphosphonium salts which… Click to show full abstract
Abstract Friedel-Crafts reaction of 1-(N-acylamino)alkyltriarylphosphonium salts with arenes or heteroarenes without the need for any catalyst provided access to a wide range of biologically interesting N-(1-arylalkyl)amides or 1-arylalkylphosphonium salts which can be of great interest in the chemistry of ylides and phosphonium ionic liquids. Depending on reaction conditions and substrate structure, the reaction can be conducted selectively with high yields toward each of the above-mentioned products. Mechanistic aspects of the above transformations were also considered.
Journal Title: Tetrahedron
Year Published: 2018
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