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Expedient synthesis of xanthones and multi-functionalized chromones from 1,1-diacyl cyclopropanes

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Abstract We report the rapid synthesis of various cycloheptane-fused chromones and an oxepine fused flavone in 5 steps from the corresponding 2-hydroxy acetophenone. Furthermore, we describe the synthesis of xanthones,… Click to show full abstract

Abstract We report the rapid synthesis of various cycloheptane-fused chromones and an oxepine fused flavone in 5 steps from the corresponding 2-hydroxy acetophenone. Furthermore, we describe the synthesis of xanthones, in moderate to good yield, from 2,3-disubstituted flavones using a Friedel Crafts alkylation strategy.

Keywords: synthesis xanthones; expedient synthesis; xanthones multi; functionalized chromones; synthesis; multi functionalized

Journal Title: Tetrahedron
Year Published: 2018

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