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Divergent synthesis of functionalized thioethers via multicomponent reaction of benzynes

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Abstract Diverse functionalized thioethers were efficiently synthesized through the multicomponent reaction of benzynes, cyclic thioethers and different nucleophiles. Both inorganic salts (KF, KCl, KBr, and KSCN) and silylated reagents (TMSCN,… Click to show full abstract

Abstract Diverse functionalized thioethers were efficiently synthesized through the multicomponent reaction of benzynes, cyclic thioethers and different nucleophiles. Both inorganic salts (KF, KCl, KBr, and KSCN) and silylated reagents (TMSCN, TMSN3, TMSCl) can be utilized as efficient nucleophiles for the reaction.

Keywords: divergent synthesis; multicomponent reaction; functionalized thioethers; synthesis functionalized; reaction benzynes

Journal Title: Tetrahedron
Year Published: 2018

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