LAUSR

Abstract Seven new diterpenoids, classified as three cembrane-type diterpenoids boscartins I-K (1–3) and four prenylaromadendrane-type diterpenoids boscartols K-N (4–7), respectively, along with nine known diterpenoids, were isolated from the gum resin of Boswellia carterii. Their structure elucidations were achieved by spectroscopic examination. All isolates were evaluated for anti-inflammatory activity against nitric oxide (NO) production and antiproliferative activity against MCF-7 human breast cancer cell in vitro. 4 and 5 exhibited potent inhibitory effects on NO production (IC50 of 2.22 and 1.10 μM, respectively), with 11 showing moderate inhibition (IC50 of 8.63 μM), and 12 and 15 demonstrated moderate antiproliferative effects against MCF-7 cell (IC50 of 9.5, and 6.3 μM, respectively).