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Abstract Cross dehydrogenative coupling (CDC) strategy has been employed for C-alkynylation of 4-thiazolidinone with terminal alkyne under copper catalysis. Present reaction involves coupling of C(sp 3 ) adjacent to sulfur… Click to show full abstract
Abstract Cross dehydrogenative coupling (CDC) strategy has been employed for C-alkynylation of 4-thiazolidinone with terminal alkyne under copper catalysis. Present reaction involves coupling of C(sp 3 ) adjacent to sulfur of 4-thiazolidinone with C(sp) of terminal alkyne under CDC strategy is unprecedented to the best of our knowledge. Significant functional group tolerance, considerable yield and DFT study for mechanism make this synthetic task more interesting and compatible.
Keywords:
dehydrogenative coupling;
thiazolidinone terminal;
cross dehydrogenative;
terminal alkyne
Journal Title: Tetrahedron
Year Published: 2019
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Journal Title: Tetrahedron
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!