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Abstract KMnO4-mediated oxidative C N bond cleavage of tertiary amines producing secondary amine was introduced, which was trapped by electrophiles (acyl chloride and sulfonyl chloride) to form amides and sulfonamides.… Click to show full abstract
Abstract KMnO4-mediated oxidative C N bond cleavage of tertiary amines producing secondary amine was introduced, which was trapped by electrophiles (acyl chloride and sulfonyl chloride) to form amides and sulfonamides. The reaction could take place at mild condition, tolerating a wide range of function groups and affording products in moderate to excellent yields.
Keywords:
bond cleavage;
tertiary amines;
oxidative bond;
kmno4 mediated;
mediated oxidative;
cleavage tertiary
Journal Title: Tetrahedron
Year Published: 2019
Link to full text (if available)
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Journal Title: Tetrahedron
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!