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ABSTRACT: A simple on water approach for the synthesis of novel tetrahydropyrimidine (THPM) derivatives has been developed under a green and sustainable fashion. For the first time, a deuterated Biginelli’s… Click to show full abstract
ABSTRACT: A simple on water approach for the synthesis of novel tetrahydropyrimidine (THPM) derivatives has been developed under a green and sustainable fashion. For the first time, a deuterated Biginelli’s hybrid was synthesized. Novel THPMs are suitable for further derivatization and could be an excellent toolkit for lead-oriented synthesis and/or cross-coupling reactions.
Keywords:
synthesis novel;
oxo tetrahydropyrimidines;
water synthesis;
novel oxo;
synthesis
Journal Title: Tetrahedron
Year Published: 2020
Link to full text (if available)
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Journal Title: Tetrahedron
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!