Photo by gabrielle_photo from unsplash
Abstract A first total synthesis of alstofonidine is described from the pentacyclic core, an advanced intermediate reported previously. The pentacyclic core facilitated putative biosynthetic congener access, thereby allowing a rapid… Click to show full abstract
Abstract A first total synthesis of alstofonidine is described from the pentacyclic core, an advanced intermediate reported previously. The pentacyclic core facilitated putative biosynthetic congener access, thereby allowing a rapid synthesis of alstofonidine from the proposed biosynthetic pathway. Besides, the model substrate to obtain a simplified bicyclic acetal portion also leveraged in accomplishing structurally complex alstofonidine effortlessly.
Keywords:
alstofonidine;
synthesis alstofonidine;
biosynthetic congener;
total synthesis;
putative biosynthetic
Journal Title: Tetrahedron
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Tetrahedron
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!