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Development of a manufacturing process for the drug fenleuton

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Abstract A new strategy for a large scale synthesis is developed and evaluated by the improvement of the current synthesis for fenleuton, a drug with important applications in leukotriene-mediated inflammatory… Click to show full abstract

Abstract A new strategy for a large scale synthesis is developed and evaluated by the improvement of the current synthesis for fenleuton, a drug with important applications in leukotriene-mediated inflammatory diseases that acts through inhibition of the 5-lipoxygenase enzyme.

Keywords: process drug; manufacturing process; drug; development manufacturing; fenleuton; drug fenleuton

Journal Title: Tetrahedron Letters
Year Published: 2017

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