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Abstract Palladium catalyzed intramolecular aminoacetoxylation of d -ribose derived alkenyl tosylsulfonamide to deliver l -deoxyallonojirimycin in an overall yield of 19%. The preliminary screening of l -deoxyallonojirimycin against carbohydrate processing… Click to show full abstract
Abstract Palladium catalyzed intramolecular aminoacetoxylation of d -ribose derived alkenyl tosylsulfonamide to deliver l -deoxyallonojirimycin in an overall yield of 19%. The preliminary screening of l -deoxyallonojirimycin against carbohydrate processing enzymes showed moderate inhibitory activity against α-glucosidase (yeast) and α-mannosidases.
Keywords:
intramolecular aminoacetoxylation;
palladium catalyzed;
alkenyl tosylsulfonamide;
derived alkenyl;
catalyzed intramolecular
Journal Title: Tetrahedron Letters
Year Published: 2017
Link to full text (if available)
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Journal Title: Tetrahedron Letters
Year Published: 2017
Link to full text (if available)
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recommendations!