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New method for the synthesis of chromeno[4,3-b]chromene derivatives via multicomponent reaction promoted by niobium pentachloride

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Abstract Chromeno[4,3-b]chromene derivatives were synthesized from multicomponent reaction between 4-hydroxycoumarin, aryl aldehyde derivatives and 1,3-cyclohexanedione promoted by niobium pentachloride. This new method is simple, cost-effective, provides good yields with good… Click to show full abstract

Abstract Chromeno[4,3-b]chromene derivatives were synthesized from multicomponent reaction between 4-hydroxycoumarin, aryl aldehyde derivatives and 1,3-cyclohexanedione promoted by niobium pentachloride. This new method is simple, cost-effective, provides good yields with good substrate generality and can be conducted in short reaction times.

Keywords: multicomponent reaction; promoted niobium; chromene derivatives; reaction; chromeno chromene; niobium pentachloride

Journal Title: Tetrahedron Letters
Year Published: 2017

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