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Competitive, substrate-dependent reductive debromination/dehydrobromination of 1,2-dibromides with triethylamine.

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The interaction of various 1,2-dibromides with NEt3 under various conditions (THF and DMF, respectively) at different temperatures was investigated. Our results from these reactions show that substrate dependent dehydrobrominations compete… Click to show full abstract

The interaction of various 1,2-dibromides with NEt3 under various conditions (THF and DMF, respectively) at different temperatures was investigated. Our results from these reactions show that substrate dependent dehydrobrominations compete with reductive debrominations. A comprehensive discussion of these competitive pathways is offered.

Keywords: reductive debromination; dehydrobromination dibromides; competitive substrate; dependent reductive; substrate dependent; debromination dehydrobromination

Journal Title: Tetrahedron letters
Year Published: 2017

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