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Five new aromatic polyketides, alternaphenols A-E (1-5), and two known compounds (6-7) were isolated from a liquid culture of Alternaria sp. (strain no. NF2198), a caterpillar associated fungus. Their structures… Click to show full abstract
Five new aromatic polyketides, alternaphenols A-E (1-5), and two known compounds (6-7) were isolated from a liquid culture of Alternaria sp. (strain no. NF2198), a caterpillar associated fungus. Their structures were determined by extensive spectroscopic analysis and single crystal X-ray crystallography. Compounds 1-7 were evaluated for their cytotoxic activities against a human skin melanoma A-375 cell line. Only compounds 4 and 5 showed weak cytotoxic activities.
Keywords:
aromatic polyketides;
associated alternaria;
polyketides caterpillar;
caterpillar associated
Journal Title: Tetrahedron Letters
Year Published: 2017
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Journal Title: Tetrahedron Letters
Year Published: 2017
Link to full text (if available)
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recommendations!