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Abstract A new benzothizole-based fluorescent probe 1 for Hg2+ recognition utilizing “ESIPT+AIE” strategy has been developed. In THF/H2O (1:1, v/v, PBS 20 mM, pH = 8.5) mixed solution, probe 1 displays rapid fluorescence… Click to show full abstract
Abstract A new benzothizole-based fluorescent probe 1 for Hg2+ recognition utilizing “ESIPT+AIE” strategy has been developed. In THF/H2O (1:1, v/v, PBS 20 mM, pH = 8.5) mixed solution, probe 1 displays rapid fluorescence responses to Hg2+ ions with high selectivity and sensitivity through Hg2+-triggered releasing of a compound possessing “ESIPT+AIE” characteristics. Cell imaging investigations indicate that probe 1 is cell permeable with low toxicity to MCF-7 cells, and applicable to detect Hg2+ ions in living MCF-7 cells.
Journal Title: Tetrahedron Letters
Year Published: 2017
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