Abstract An efficient recyclable [bmIm]OH catalyzed and aqua mediated eco-compatible synthesis of biologically versatile 2,8 dioxacyclopenta [ a ] inden-3-one derivatives. Combination of ionic liquid and water has emerged out… Click to show full abstract
Abstract An efficient recyclable [bmIm]OH catalyzed and aqua mediated eco-compatible synthesis of biologically versatile 2,8 dioxacyclopenta [ a ] inden-3-one derivatives. Combination of ionic liquid and water has emerged out as a powerful synthetic tool for constructing C–C, C–S and C–O bonds. Disclosed methodology for introducing broad range of 2-iodophenols, 2-iodothiophenols and tetronic acid in basic ionic liquid with predictable high yield will catch the attention of synthetic chemists. This protocol has documented the notable advances and the applications of ionic liquid in heterocyclic synthesis. The chosen strategy illustrates important issues regarding scope, reactivity, product yield, reaction time, reuse and recyclability that will help in designing new synthetic routes for other heterocyclic synthesis.
               
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