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Abstract The unique features of the pentafluorosulfanyl (SF5) group have made it renowned as a “super trifluoromethyl (CF3)” group. Owing to the big success of CF3-containing heteroaromatic compounds in medicinal… Click to show full abstract
Abstract The unique features of the pentafluorosulfanyl (SF5) group have made it renowned as a “super trifluoromethyl (CF3)” group. Owing to the big success of CF3-containing heteroaromatic compounds in medicinal chemistry, agro-chemistry and material sciences, SF5-substituted heteroaromatic compounds have gained a lot of attention in very recent years as novel and potential candidates in these fields. However, the synthetic methodology for SF5-substituted heteroaromatic compounds is still highly limited. This digest highlights the recent, rapid, and significant advances made in the synthesis of SF5-heteroaromatics.
Journal Title: Tetrahedron Letters
Year Published: 2017
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