Photo by cheungyin from unsplash
A neo-clerodane diterpenoid, salvihispin A (1), as well as its glycoside, salvihispin A-2-O-beta-D-3-keto-glucopyranoside (2) were isolated from the aerial parts of Salvia hispanica. Compound 2 possessed an unusual 3-keto-glucopyranoside moiety.… Click to show full abstract
A neo-clerodane diterpenoid, salvihispin A (1), as well as its glycoside, salvihispin A-2-O-beta-D-3-keto-glucopyranoside (2) were isolated from the aerial parts of Salvia hispanica. Compound 2 possessed an unusual 3-keto-glucopyranoside moiety. Their structures and absolute configurations were elucidated by extensive spectroscopic methods and confirmed by single crystal X-ray diffraction. Salvihispin A (1) and its glycoside (2) enhanced the neurite outgrowth of NGF-mediated PC12 cells at a concentration of 10 mu M. (C) 2017 Elsevier Ltd. All rights reserved.
Journal Title: Tetrahedron Letters
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!