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Guanidine organocatalysis for enantioselective carbon-heteroatom bond-forming reactions

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Abstract Guanidine-containing molecules have been employed as organocatalysts, and chiral guanidines have been widely explored as catalysts for mediating asymmetric reactions by constructing an asymmetric reaction environment. Currently, many guanidine-catalyzed… Click to show full abstract

Abstract Guanidine-containing molecules have been employed as organocatalysts, and chiral guanidines have been widely explored as catalysts for mediating asymmetric reactions by constructing an asymmetric reaction environment. Currently, many guanidine-catalyzed asymmetric reactions are available, and some excellent reviews have appeared. In this Digest, we focused on recent progress in the guanidine-catalyzed asymmetric construction of C N, C O, C P, and C S bonds, especially developments since 2010.

Keywords: carbon heteroatom; guanidine organocatalysis; heteroatom bond; organocatalysis enantioselective; enantioselective carbon; bond forming

Journal Title: Tetrahedron Letters
Year Published: 2017

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