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Abstract A 1H NMR analysis method that detects enantiomers of molecules bearing a primary amino group has been developed. The method uses a β-keto ester-derived probe that forms enamines with… Click to show full abstract
Abstract A 1H NMR analysis method that detects enantiomers of molecules bearing a primary amino group has been developed. The method uses a β-keto ester-derived probe that forms enamines with the amines and is able to discriminate enantiomers of functionalized amines and amines that have chiral centers at positions remote from the amine group.
Keywords:
enantiomers chiral;
detection enantiomers;
keto ester;
chiral primary;
nmr analysis
Journal Title: Tetrahedron Letters
Year Published: 2018
Link to full text (if available)
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Journal Title: Tetrahedron Letters
Year Published: 2018
Link to full text (if available)
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recommendations!