Abstract We demonstrate that copper diisobutyl-t-butoxyaluminum hydride, readily prepared from lithium diisobutyl-t-butoxyaluminum hydride and CuI, effectively and chemoselectively reduces tertiary amides over esters at ambient temperature, affording the corresponding aldehydes… Click to show full abstract
Abstract We demonstrate that copper diisobutyl-t-butoxyaluminum hydride, readily prepared from lithium diisobutyl-t-butoxyaluminum hydride and CuI, effectively and chemoselectively reduces tertiary amides over esters at ambient temperature, affording the corresponding aldehydes in excellent yields.
Keywords:
butoxyaluminum hydride;
copper diisobutyl;
diisobutyl butoxyaluminum;
tertiary amides
Journal Title: Tetrahedron Letters
Year Published: 2018
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Journal Title: Tetrahedron Letters
Year Published: 2018
Link to full text (if available)
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recommendations!