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A highly efficient TEMPO mediated oxidation of sugar primary alcohols into uronic acids using 1-chloro-1,2-benziodoxol-3(1H)-one at room temperature

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Abstract Oxidation of various sugar primary alcohols into corresponding uronic acids was demonstrated using 1-chloro-1,2-benziodoxol-3(1H)-one and TEMPO. The reaction proceeds at room temperature in good to excellent yields. Primary alcohols… Click to show full abstract

Abstract Oxidation of various sugar primary alcohols into corresponding uronic acids was demonstrated using 1-chloro-1,2-benziodoxol-3(1H)-one and TEMPO. The reaction proceeds at room temperature in good to excellent yields. Primary alcohols get oxidized selectively over the secondary alcohols under mild reaction conditions.

Keywords: sugar primary; benziodoxol one; chloro benziodoxol; primary alcohols; uronic acids; using chloro

Journal Title: Tetrahedron Letters
Year Published: 2018

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