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A convenient synthesis of (E)-conjugated polyene sulfonyl derivatives with excellent stereospecificity

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Abstract A highly selective synthesis of conjugated polyene sulfonyl derivatives is described via the elimination of disulfonyl chloride with readily accessible raw material dihaloalkane. The protocol offers a convenient way… Click to show full abstract

Abstract A highly selective synthesis of conjugated polyene sulfonyl derivatives is described via the elimination of disulfonyl chloride with readily accessible raw material dihaloalkane. The protocol offers a convenient way to form sulfonamides, sulfonates and even sulfones. Furthermore, this method was manipulated under mild condition with simple operation in high yield to afford only trans products.

Keywords: sulfonyl derivatives; synthesis conjugated; conjugated polyene; polyene sulfonyl; convenient synthesis

Journal Title: Tetrahedron Letters
Year Published: 2018

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