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Nonstabilized azomethine ylides in the synthesis of aryl cucurbitine derivatives

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Abstract Nonstabilized azomethine ylides react with 4-arylidene-2-phenyloxazol-5(4H)-ones to form diazaspiro[4.4]nonenes, which were hydrolyzed to aryl cucurbitine derivatives in 35–67% overall yield. Click to show full abstract

Abstract Nonstabilized azomethine ylides react with 4-arylidene-2-phenyloxazol-5(4H)-ones to form diazaspiro[4.4]nonenes, which were hydrolyzed to aryl cucurbitine derivatives in 35–67% overall yield.

Keywords: ylides synthesis; aryl cucurbitine; azomethine ylides; nonstabilized azomethine; cucurbitine derivatives

Journal Title: Tetrahedron Letters
Year Published: 2019

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