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Abstract A general method for the synthesis of 1,2,3,4-tetrasubstituted pyrroles by [NMPH]CH3SO3 is reported. A full factorial design was performed in order to obtain a more robust and statistically correct… Click to show full abstract
Abstract A general method for the synthesis of 1,2,3,4-tetrasubstituted pyrroles by [NMPH]CH3SO3 is reported. A full factorial design was performed in order to obtain a more robust and statistically correct optimum condition. The products were obtained in moderate to excellent yields. The developed methodology is very simple, cost-effective, and applicable for tri- and tetra-component reactions.
Keywords:
tetrasubstituted pyrroles;
pot multicomponent;
synthesis tetrasubstituted;
nmph ch3so3;
one pot
Journal Title: Tetrahedron Letters
Year Published: 2019
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Journal Title: Tetrahedron Letters
Year Published: 2019
Link to full text (if available)
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recommendations!