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Abstract The aim of this work is to investigate the three-component reaction of 6-aminopenicillinic acid, aldehydes and ammonium acetate. The work was used SiO2-H2SO4 as a catalyst to promote the… Click to show full abstract
Abstract The aim of this work is to investigate the three-component reaction of 6-aminopenicillinic acid, aldehydes and ammonium acetate. The work was used SiO2-H2SO4 as a catalyst to promote the reaction under solvent-free conditions. A series of 5,5-dimethyl-2-(2-aryl-1H-imidazol-5-yl)-2,5-dihydrothiazole derivatives were obtained as the main product by this method.
Keywords:
derivatives containing;
imidazole derivatives;
preparation imidazole;
new strategy;
containing thiazole;
strategy preparation
Journal Title: Tetrahedron Letters
Year Published: 2019
Link to full text (if available)
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Journal Title: Tetrahedron Letters
Year Published: 2019
Link to full text (if available)
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recommendations!