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Abstract The fungal metabolites rubrolide R and S were synthesized in concise, entirely stereoselective fashion through the combined use of bromine-stereodirected vinylogous aldol condensation (SVAC) and Suzuki cross-coupling. A bioinspired,… Click to show full abstract
Abstract The fungal metabolites rubrolide R and S were synthesized in concise, entirely stereoselective fashion through the combined use of bromine-stereodirected vinylogous aldol condensation (SVAC) and Suzuki cross-coupling. A bioinspired, high-yield conversion of rubrolide R to rubrolide S is also reported.
Keywords:
concise stereocontrolled;
influenza rubrolides;
anti influenza;
modular syntheses;
syntheses anti;
stereocontrolled modular
Journal Title: Tetrahedron Letters
Year Published: 2019
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Journal Title: Tetrahedron Letters
Year Published: 2019
Link to full text (if available)
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recommendations!